west syndrome การใช้

• Sometimes West syndrome turns into a focal or other generalised epilepsy.
• Sometimes multiple children within the same family develop West syndrome.
• As many as 6 out of 10 children with West syndrome suffer from epilepsy later in life.
• Together with developmental regression and infantile spasms, hypsarrhythmia is one of the diagnostic criteria for West syndrome.
• Once more, the etiology of each individual case of West syndrome must be considered when debating cause and effect.
• The prognosis for children with idiopathic West syndrome are mostly more positive than for those with the cryptogenic or symptomatic forms.
• However, in a physician survey conducted December 2004, only 28 % of Lennox Gastaut and West syndrome patients improved on zonisamide.
• There is renewed interest in sultiame's other potential uses, e . g ., in West syndrome and other refractory epilepsies
• As in West syndrome, LGS result from idiopathic, symptomatic, or cryptogenic causes, and many patients first have West syndrome.
• As in West syndrome, LGS result from idiopathic, symptomatic, or cryptogenic causes, and many patients first have West syndrome.
• There are known cases in which West syndrome appears in successive generations in boys; this has to do with X-chromosomal heredity.
• Vigabatrin is also indicated for monotherapy use in secondarily generalized tonic-clonic seizures, partial seizures, and in infantile spasms due to West syndrome.
• It has been found to be more effective than clonazepam in the treatment of West syndrome, which is an age-dependent epilepsy, affecting the very young.
• Treatment differs in each individual case and depends on the cause of the West syndrome ( etiological classification ) and the state of brain development at the time of the damage.
• West syndrome in modern usage is the triad of infantile spasms, a pathognomonic EEG pattern ( called hypsarrhythmia ), and developmental regression-although the international definition requires only two out of these three elements.
• Statistically, 5 out of every 100 children with West syndrome do not survive beyond five years of age, in some cases due to the cause of the syndrome, in others for reasons related to their medication.
• At one time, mutations in the CDKL5 gene were said to cause a disorder called X-linked infantile spasm syndrome ( ISSX ) or West syndrome . but this research established CDKL5 disorder as a distinct clinical entity.
• In other cases, however, treatment of West syndrome is relatively difficult and the results of therapy often dissatisfying; for children with symptomatic and cryptogenic West syndrome, the prognosis is generally not positive, especially when they prove resistant to therapy.
• In other cases, however, treatment of West syndrome is relatively difficult and the results of therapy often dissatisfying; for children with symptomatic and cryptogenic West syndrome, the prognosis is generally not positive, especially when they prove resistant to therapy.
• Permanent damage often associated with West syndrome in the literature include cognitive disabilities, learning difficulties and behavioural problems, cerebral palsy ( up to 5 out of 10 children ), psychological disorders and often autism ( in around 3 out of 10 children ).